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All eyes turn for a fascinating top-flight matchup as table-toppers Arsenal host struggling Wolverhampton Wanderers to the their home ground.

Confirmed Sides

Mikel Arteta's side have introduced three changes following the XI that suffered a narrow loss at Aston Villa in their previous outing. The French defender, the Swedish striker and the Brazilian winger all come into the starting eleven. Martin Ødegaard and Mikel Merino drop to the bench, while Riccardo Calafiori is not involved. The centre-back returns after missing a run of games due to injury.

Wolves also have made three adjustments to their lineup after being heavily defeated 4-1 at Molineux by United on Monday evening. Matt Doherty, João Gomes and Hwang Hee-chan start. Ki-Jana Hoever and Jhon Arias drop to the bench, while Jean‐Ricner Bellegarde misses out altogether.

Starting Elevens

Arsenal: Raya, White, Saliba, Hincapie, Timber, Eze, Zubimendi, Rice, Saka, Gyokeres, Martinelli.
Subs: Arrizabalaga, Odegaard, Gabriel Jesus, Norgaard, Trossard, Madueke, Nwaneri, Merino, Lewis-Skelly.

Wolverhampton Wanderers: Johnstone, Mosquera, Agbadou, Toti Gomes, Doherty, Joao Gomes, Andre Trindade, Krejci, Wolfe, Larsen, Hwang.
Substitutes: Tchatchoua, Mane, Lopez, Hoever, Chirewa, Arokodare, Arias, Santiago Bueno, Jose Sa.

Match Official: Robert Jones
Video Assistant Referee: John Brooks

The Setup

Welcome! And I mean, let's be honest …

The standings reveals a striking story. Arsenal sit proudly at the top of the Premier League, while Wolves anchor the league.

… yet while this will be the 42nd time the Premier League leaders have played the side propping up the division – with 30 out of 41, with seven draws – who are responsible for two of the four historical shocks? Why, Wolverhampton Wanderers, of course! Therefore, although Mikel Arteta will undoubtedly be anticipating another victory, Rob Edwards must know that underdogs occasionally come off, and anything is possible. Kick-off is at 8pm GMT. It’s on!

^{(The remaining last-over-first wins in the modern top-flight era are Oldham’s 1-0 win over United in March 1993, and Tottenham Hotspur – admittedly, this one sounds a bit weird - defeating Liverpool in November 2008.)}